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MFM FELLOWSHIP FACULTY
PERCY PACORA, MD, MPH

Wayne State University/Perinatology Research Branch - Percy Macora, MD, MPHTitle

  • Associate Professor- research. Department of Obstetrics and Gynecology. Wayne State University. Full-Time Status.

Education and Training

  • M.D. Universidad Nacional Mayor de San Marcos, Faculty of Medicine, Lima, Peru
  • Obstetrician and Gynecologist. Universidad Nacional Mayor de San Marcos, Faculty of Medicine, Lima, Peru
  • Fellow in Diabetes and Pregnancy. National Diabetes Control Program, Maternal Fetal Division, Johns Hopkins Hospital, Baltimore, Maryland, and Women and Infants Hospital of Rhode Island Providence, Rhode Island.
  • Research Fellow. Perinatology Research Branch, NICHD/NIH/DHHS
  • Mental Health and Post-Conflict Recovery.Harvard Program in Refugee Trauma, Department of Psychiatry. Massachusetts General Hospital, Cambridge, Massachusetts, USA
  • Master in Public and Global Health. Universidad Peruana Cayetano Heredia, Lima, Peru

Research Accomplishments

  • To stablish diagnostic criteria for diagnosing  prediabetes and diabetes mellitus  in pregnancy
  • To stablish that placental genes variations and maternal cardiovascular and metabolic genes may be associated with placental abruption.
  • To determine the mechanism of structurally normal stillbirth
  • Authored and co-author more than 80 peer reviewed publications.

Awards and Recognitions

  • First National Award in Clinical Investigation. Peruvian Diabetes Association (ADIPER) 2015. Lima, Perú
  • First Award in Clinical Investigation of Obstetrics and Gynecology .Hospital Madre-Niño "San Bartolomé," Lima 2015, Perú
  • Second  Award in Clinical Investigation on Human Health Peruvian Japanese Society. Lima 2-14, Peru
  • University Book Award for "Crecimiento Fetaly Neonatal en el Peru" (Fetal Growth and Development in Perú). Lima 2007, Peru.
  • First Award in Clinical Investigation of Obstetrics and Gynecology. 30th Anniversary of Hospital Madre-Niño "San Bartolomé," Lima 1991, Perú
  • First Award at the 3rd Contest of Clinical Investigation Peruvian American Medical Society and Asociación Médica   Peruano-Norteamericana, Lima 1991, Perú.
  • Second Award in Premio Roussel de Residentado Medico.This award recognizes research excellence and achievement in Medical Residency by Roussel Laboratory.Lima, 1987, Peru.
  • First Award in Clinical Investigation at II Congreso Peruano de Endocrinología, Lima 1985, Perú   

Research Interests

  • Fetal death
  • Prediabetes and diabetes in pregnancy
  • Obesity and pregnancy
  • Prevention and long -term consequences of obstetrical syndromes

Selected Publications

  • Pacora P, Romero R, Jaiman S, Erez O, Bhatti G, Panaitescu B,Benshalom-Tirosh N, Jung EJ, Hsu CD, Hassan SS, Yeo L, Kadar N. Mechanisms of death in structurally normal stillbirths. J Perinat Med. 2019 Feb 25;47(2):222-240.
  • Chahal HS, Gelaye B, Mostofsky E, Sanchez SE, Mere JF, Mercado FG, Pacora P,Williams MA. Physical Exertion Immediately Before Early Preterm Delivery: A Case-Crossover Study. Epidemiology. 2019 Jul;30(4):582-589.
  • Chahal HS, Gelaye B, Mostofsky E, Sanchez SE, Mere JF, Mercado FG, Pacora P, Williams MA. Physical Exertion Immediately Before Early Preterm Delivery: A Case-Crossover Study. Epidemiology. 2019 Jul;30(4):582-589.
  • Pacora P, Romero R, Erez O, Maymon E, Panaitescu B, Kusanovic JP, Tarca AL, Hsu CD, Hassan SS. The diagnostic performance of the beta-glucan assay in the detection of intra-amniotic infection with Candida species. J Matern Fetal Neonatal Med. 2019 May;32(10):1703-1720.
  • Larrabure-Torrealva GT, Martinez S, Luque-Fernandez MA, Sanchez SE, Mascaro PA, Ingar H, Castillo W, Zumaeta R, Grande M, Motta V, Pacora P, Gelaye B, Williams MA. Prevalence and risk factors of gestational diabetes mellitus: findings from a universal screening feasibility program in Lima, Peru. BMC Pregnancy Childbirth. 2018 Jul 18;18(1):303.
  • Chahal HS, Gelaye B, Mostofsky E, Sanchez SE, Mittleman MA, Maclure M, Pacora P, Torres JA, Romero R, Ananth CV, Williams MA. Physical Exertion Immediately Prior to Placental Abruption: A Case-Crossover Study. Am J Epidemiol. 2018 Oct 1;187(10):2073-2079.
  • Tarca AL, Romero R, Benshalom-Tirosh N, Than NG, Gudicha DW, Done B, Pacora P, Chaiworapongsa T, Panaitescu B, Tirosh D, Gomez-Lopez N, Draghici S, Hassan SS,Erez O. The prediction of early preeclampsia: Results from a longitudinalproteomics study. PLoS One. 2019 Jun 4;14(6):e0217273.
  • Kabiri D, Romero R, Gudicha DW, Hernandez-Andrade E, Pacora P, Benshalom-Tirosh N, Tirosh D, Yeo L, Erez O, Hassan SS, Tarca AL. Prediction of adverse perinatal outcomes by fetal biometry: a comparison of customized and population-based standards. Ultrasound Obstet Gynecol. 2019 Apr 22. doi:10.1002/uog.20299.
  • Gomez-Lopez N, Romero R, Panaitescu B, Miller D, Zou C, Gudicha DW, Tarca AL, Para R, Pacora P, Hassan SS, Hsu CD. Gasdermin D: in vivo evidence of pyroptosis in spontaneous labor at term. J Matern Fetal Neonatal Med. 2019 May 6:1-11. doi: 10.1080/14767058.2019.1610740. [Epub ahead of print] PubMed PMID: 31006293.
  • Gomez-Lopez N, Roberto R, Galaz J, Xu Y, Panaitescu B, Slutsky R, Motomura K, Gill N, Para R, Pacora P, Jung E, Hsu CD. Cellular immune responses in amniotic fluid of women with preterm labor and intra-amniotic infection or intra-amniotic  inflammation. Am J Reprod Immunol. 2019 Jul 19:e13171. doi: 10.1111/aji.13171.
  • Winters AD, Romero R, Gervasi MT, Gomez-Lopez N, Tran MR, Garcia-Flores V, Pacora P, Jung E, Hassan SS, Hsu CD, Theis KR. Does the endometrial cavity have a molecular microbial signature? Sci Rep. 2019 Jul 9;9(1):9905.
  • Theis KR, Romero R, Winters AD, Greenberg JM, Gomez-Lopez N, Alhousseini A,Bieda J, Maymon E, Pacora P, Fettweis JM, Buck GA, Jefferson KK, Strauss JF 3rd, Erez O, Hassan SS. Does the human placenta delivered at term have a microbiota?Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics. Am J Obstet Gynecol. 2019 Mar;220(3):267.e1-267.e39.
  • Gomez-Lopez N, Romero R, Maymon E, Kusanovic JP, Panaitescu B, Miller D,Pacora P, Tarca AL, Motomura K, Erez O, Jung E, Hassan SS, Hsu CD. Clinical chorioamnionitis at term IX: in vivo evidence of intra-amniotic inflammasome activation. J Perinat Med. 2019 Apr 24;47(3):276-287.
  • Romero R, Gomez-Lopez N, Kusanovic JP, Pacora P, Panaitescu B, Erez O, Yoon BH. Clinical Chorioamnionitis at Term: New Insights into the Etiology,Microbiology, and the Fetal, Maternal and Amniotic Cavity Inflammatory Responses.Nogyogyaszati Szuleszeti Tovabbkepzo Szemle. 2018 Jun;20(3):103-112.
  • Romero R, Kim YM, Pacora P, Kim CJ, Benshalom-Tirosh N, Jaiman S, Bhatti G, Kim JS, Qureshi F, Jacques SM, Jung EJ, Yeo L, Panaitescu B, Maymon E, Hassan SS,Hsu CD, Erez O. The frequency and type of placental histologic lesions in term pregnancies with normal outcome. J Perinat Med. 2018 Aug 28;46(6):613-630.
  • Gomez-Lopez N, Romero R, Panaitescu B, Leng Y, Xu Y, Tarca AL, Faro J, Pacora P, Hassan SS, Hsu CD. Inflammasome activation during spontaneous preterm labor with intra-amniotic infection or sterile intra-amniotic inflammation. Am J Reprod Immunol. 2018 Nov;80(5):e13049. doi: 10.1111/aji.13049.
  • Varrey A, Romero R, Panaitescu B, Miller D, Chaiworapongsa T, Patwardhan M,Faro J, Pacora P, Hassan SS, Hsu CD, Gomez-Lopez N. Human β-defensin-1: A natural antimicrobial peptide present in amniotic fluid that is increased in spontaneous preterm labor with intra-amniotic infection. Am J Reprod Immunol. 2018 Oct;80(4):e13031.
  • Panaitescu B, Romero R, Gomez-Lopez N, Pacora P, Erez O, Vadillo-Ortega F, Yeo L, Hassan SS, Hsu CD. ELABELA plasma concentrations are increased in women with late-onset preeclampsia. J Matern Fetal Neonatal Med. 2018 Jul 22:1-11.
  • Conde-Agudelo A, Romero R, Da Fonseca E, O'Brien JM, Cetingoz E, Creasy GW, Hassan SS, Erez O, Pacora P, Nicolaides KH. Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short cervix: updated indirect comparison meta-analysis. Am J Obstet Gynecol. 2018 Jul;219(1):10-25.
  • Tarca AL, Romero R, Gudicha DW, Erez O, Hernandez-Andrade E, Yeo L, Bhatti G,Pacora P, Maymon E, Hassan SS. A new customized fetal growth standard for African American women: the PRB/NICHD PMC5815382Detroit study. Am J Obstet Gynecol. 2018 Feb;218(2S):S679-S691.e4.
  • Docheva N, Romero R, Chaemsaithong P, Tarca AL, Bhatti G, Pacora P, Panaitescu B, Chaiyasit N, Chaiworapongsa T, Maymon E, Hassan SS, Erez O. The profiles of soluble adhesion molecules in the "great obstetrical syndromes"(). J Matern Fetal Neonatal Med. 2019 Jul;32(13):2113-2136.
  • Pacora P. "Diagnostic criteria for prediabetes using oral glucosa tolerance test in pregnancy" Master of Public and Global Health's Thesis . Universidad Peruana Cayetano Heredia, Lima 2016, Peru.
  • Qiu C, Gelaye B, Denis M, Tadesse MG, Enquobahrie DA, Ananth CV, Pacora PN, Salazar M, Sanchez SE, Williams MA. Placental genetic variations in circadian clock-related genes increase the risk of placental abruption. Int J Mol Epidemiol Genet. 2016 Mar 23;7(1):32-40.
  • Workalemahu T, Enquobahrie DA, Moore A, Sanchez SE, Ananth CV, Pacora PN, Liang L, Salazar M, Williams MA. Genome-wide and candidate gene association studies of placental abruption. Int J Mol Epidemiol Genet. 2013 Sep 12;4(3):128-39.
  • Moore A, Enquobahrie DA, Sanchez SE, Ananth CV, Pacora PN, Williams MA. A genome-wide association study of variations in maternal cardiometabolic genes and risk of placental abruption. Int J Mol Epidemiol Genet. 2012;3(4):305-13.
  • Pacora P, Romero R, Chaiworapongsa T, Kusanovic JP, Erez O, Vaisbuch E, Mazaki-Tovi S, Gotsch F, Jai Kim C, Than NG, Yeo L, Mittal P, Hassan SS. Amniotic fluid angiopoietin-2 in term and preterm parturition, and intra-amniotic infection/inflammation. J Perinat Med. 2009;37(5):503-11.
  • Pacora P, Maymon E, Gervasi MT, Gomez R, Edwin SS, Yoon BH, Romero R. Lactoferrin in intrauterine infection, human parturition, and rupture of fetal membranes. Am J Obstet Gynecol. 2000 Oct;183(4):904-10.
  • Pacora P, Romero R, Maymon E, Gervasi MT, Gomez R, Edwin SS, Yoon BH. Participation of the novel cytokine interleukin 18 in the host response to intra-amniotic infection. Am J Obstet Gynecol. 2000 Nov;183(5):1138-43.
  • Pacora P, Chaiworapongsa T, Maymon E, Kim YM, Gomez R, Yoon BH, Ghezzi F,Berry SM, Qureshi F, Jacques SM, Kim JC, Kadar N, Romero R. Funisitis and chorionic vasculitis: the histological counterpart of the fetal inflammatory response syndrome. J Matern Fetal Neonatal Med. 2002

Courses

  • Obstetrics, labor and delivery , obstetrical emergencies, thesis.