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IMPORTANT POINTS & DISCOVERIES

  • Intra-amniotic infection and/or inflammation can lead to the Fetal Inflammatory Response Syndrome (FIRS) and is a major mechanism of disease responsible for numerous perinatal and infant morbidities including, neurologic handicap and cerebral palsy
  • Characterization of the role of adipokines in normal pregnancy, preeclampsia, small for gestational age neonates, gestational diabetes, pyelonephritis, and spontaneous preterm labor
  • Identification of placental growth hormone in the fetal circulation with novel implications for fetal growth
  • The use of both cervical length and fetal fibronectin improves the prediction of preterm delivery in patients with preterm labor and intact membranes
  • Failure of physiologic transformation of the spiral arteries in patients with preterm labor and intact membranes