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IMPORTANT POINTS & DISCOVERIES

HLA-DR+ Fibrocytes (red) migrating through the umbilical vein into the
Wharton’s jelly of the umbilical cord (green: all the nuclei)

 

  • Involvement of fetal macrophages and maternal T cells as well as the systemic response of both mother and fetus in Villitis of Unknown Etiology
  • Novel role of fibrocytes in human feto-maternal development
  • Distribution of immunophenotypically distinct macrophages at the feto-maternal interface