Donal S. O'Leary, Ph.D.
Donal S. O'Leary, Ph.D., is a professor of physiology and Director of Cardiovascular Research. A graduate of Miami University (B.A.) and The University of Texas Health Science Center at San Antonio (Ph.D.), Dr. O'Leary is a cardiovascular physiologist interested in the integrative control of the cardiovascular system at rest and during stress.
Dr. O'Leary's research is funded via the National Institute of Health, Heart, Lung and Blood Institute and the Veterans Administration and is focused on understanding the neural and hormonal mechanisms of control of arterial blood pressure, heart rate, cardiac output and regional blood flow during dynamic exercise. His recent findings include determining the relative roles of the arterial baroreflex and the muscle metaboreflex (reflex responses to ischemia of active skeletal muscle) in the control of the cardiovascular system in normal and pathophysiological states such as congestive heart failure. Dr. O'Leary is also currently investigating the role of purinergic mechanisms within the nucleus tractus solaritus in cardio-respiratory homeostasis, regional blood flow and peripheral sympathetic nerve activity. The goals of these studies are to elucidate further the relative roles of cardiovascular reflexes in the control of the cardiovascular system, their interactions, and their mechanisms of action.
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